Excipients By Design
We are working on the synthesis of novel polymers for use as excipients and of synthetic modification of naturally occurring polymers, for use in drug delivery.
Examples include novel approaches to the synthesis and physicochemical characterisation of dendrimers, nanoparticles and SMART microgel polymers; research includes investigations into the stability of technologically important colloidal and particulate formulations, e.g. metered dose inhalers.
Publications
Cornelius, V. J., Snowden, M. J., and Mitchell, J. C. (2005) Polymeric films, a novel oral dosage form. Industrial Pharmacy, 7.
Gibson, G. H., Auffret, A. D., Humphries, M. J., Mitchell, J. C., and Snowden, M. J. (2005) Synthesis and characterisation of hydrophobically modified pullulan. British Pharmaceutical Conference, Manchester UK, September, 2005. Journal of Pharmacy and Pharmacology, 57. ISSN 0022-3573.
Smith, J. S., MacRae, R. J., and Snowden, M. J. (2005) Effect of SBE7-beta-cyclodextrin complexation on carbamazepine release from sustained release beads. Eur. J. Pharmaceutics and Biopharmaceutics, 60 (73).