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Professor Frank Pullen

Francis Pullen

Professor of Pharmaceutical Analysis

Room: Grenville 119

Email: frank.pullen@gre.ac.uk

Tel: 020 8331 8225
Fax: 020 8331 9805

Professor Frank Pullen




Profile

Professor Frank Pullen has 30 years experience in Organic mass spectrometry within the pharmaceutical industry, an in depth knowledge in Drug Discovery and Development and published in peer reviewed journals. 

He is on the editorial board for the journal Rapid Communications in Mass Spectrometry and also a member of the EPSRC grant review college. 

Frank is currently the holder of the British Mass Spectrometry Lecturship; a position that is bestowed for a 1 year duration.

Professor Pullen became the Director of Research & Enterprise (Enterprise) in the School of Science in April 2010.

Publications

Soft or Hard ionisation? Investigation of metastable gas temperature effect on Direct Analysis in Real Time of Voriconazole.   C Lapthorn, F Pullen; Eu J Mass Spectrom 15, 587-593 2009

Can Density Functional Theory(DFT) be used as an aid to a deeper understanding of MSMS fragmentation pathways?  A Alex, S Harvey, T Parsons, F Pullen, P Wright Rapid Commun Mass Spectrom  23: 2619-2627 2009

Ionisation in the absence of high voltage using SFC-MS: a possible route to increased signal
M Thite, R Boughtflower, J Caldwell, S Richardson, L Hitzel, S Lane, P Holyoak, F Pullen, G J Langley  Rapid Commun Mass Spectrom 22, 3673-3682  2008

Using calculated molecular descriptors to predict retention of sulphonamides in supercritical fluid chromatography.  A Cazenave, R Boughtflower, J Caldwell, L Hitzel, S Lane, P Holyoak, F Pullen, G J Langley  J Chrom. A.  1189, 254-265  2008

Gas chromatography/flame ionisation detection mass spectrometry for the detection of endogenous urine metabolites for metabonomic studies and its use as a complimentary tool to NMR.  S Fancy, O Beckonert, G Darbon, W Yabsley, R Walley, D Baker, G Perkins, F Pullen, K Rumpel  Rapid Commun Mass Spectrom. 20 2271-2280  2006

Probing noncovalent protein-ligand interactions of cGMP-dependant protein kinase using electrospray ionisation time of flight mass spectrometry.  A Heck, M Pinkse, F Pullen, K Rumpel.  J.Am.Soc. Mass Spectrom. 15 1392-1399 2004

Fragmentation pathways of sulphonamides under electrospray tandem mass spectrometric conditions.  K Klagou, F Pullen, M Harrison, A Organ, A Firth, G J Langley Rapid Commun Mass Spectrom 17 2373-2379  2003

Approaches towards the automated interpretation and prediction of electrospray tandem mass spectrometry spectra of non peptidic combinatorial compounds.  K Klagou F Pullen, M Harrison, A Organ, A Firth, G J Langley.  Rapid Commun Mass Spectrom  17, 1163-1168, 2003